ABSTRACT
Abstract Infantile hemangioma is the most common pediatric vascular tumor, with the following risk factors: low birth weight, prematurity, white skin, female gender, multiparity and advanced maternal age. The use of oral and topical beta-blockers, although recent, has emerged as the first line of treatment, with superior safety and efficacy to previously used therapies, such as corticosteroids and surgeries. This report describes two cases of nasal tip infantile hemangioma, treated with oral propranolol. Both presented excellent therapeutic responses.
Subject(s)
Humans , Female , Infant , Propranolol/administration & dosage , Nose Neoplasms/drug therapy , Adrenergic beta-Antagonists/administration & dosage , Hemangioma/drug therapy , Nose Neoplasms/pathology , Administration, Oral , Treatment Outcome , Hemangioma/pathologyABSTRACT
Abstract Nasal type extranodal NK/T-cell lymphoma is a distinct entity according to the World Health Organization classification. Although 60% to 90% of patients with this disease present with a destructive mass in the midline facial tissues, it may also primarily or secondarily involve extranasal sites, like the skin. We report the case of a 77-year-old patient that came to our department with erythematous plaques of the right leg and eczematous lesions of the trunk. These lesions were biopsied and the patient was diagnosed with extranodal NK/T-cell lymphoma, nasal type. He was treated with multi-agent systemic chemotherapy but died 5 months after diagnosis. This case highlights the rarity and variability of cutaneous features of this disease and its aggressive course and poor prognosis.
Subject(s)
Humans , Male , Aged , Skin Neoplasms/pathology , Nose Neoplasms/pathology , Lymphoma, Extranodal NK-T-Cell/pathology , Neoplasms, Multiple Primary/pathology , Skin/pathology , Skin Neoplasms/drug therapy , Vincristine/therapeutic use , Biopsy , Prednisone/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Doxorubicin/therapeutic use , Nose Neoplasms/drug therapy , Fatal Outcome , Cyclophosphamide/therapeutic use , Lymphoma, Extranodal NK-T-Cell/drug therapy , Neoplasms, Multiple Primary/drug therapyABSTRACT
Se presenta el caso de un paciente, mestizo masculino de 39 años de edad, que es visto en consulta por sangramiento nasal. Al examen físico se detecta masa tumoral que ocupa la fosa nasal izquierda. Se toma muestra para biopsia informándose la presencia de un cordoma de localización nasal. Se realizan complementarios correspondientes y se indica terapéutica oportuna...